Tag: heart

A Ghost Heart

By Anupum Pant

Before I begin, I’m happy to announce that Awesci’s feed has been featured on a smartphone app, Dabblr. I covered it a couple of days back in the interviews section. If you missed it, you might want to know what Dabblr can do and why you should use it, especially if you are a student. 

At any given time, thousands of people are there on the heart transplant waiting list. Some of these people are eventually able to find a donor, while others aren’t able to. Hundreds of people who fail to find a donor, die every year. It’s a grim state, but little can be done to change it. Texas Heart Institute (THI) had a solution for this problem – use a Pig’s heart.

(There have been cases where people have survived for some time on artificial hearts too. It’s incredible how these things work.)

A pig’s heart is a lot like our own, in shape, size and function. Of course it can’t be just taken away from a pig and installed in a human. Or people from ancient times would have done it. The researchers from THI proposed this – make a ghost heart out of it first.

For making a “ghost heart”  – a kind of a structural scaffolding – they used a simple soap solution. Once they washed the pig heart in it and may be after some other processing, they had a pure protein scaffolding, stripped off of all living cells (decellularized), which could be customized and could be used to grow a custom heart for a specific human being – by using the patient’s bone-marrow stem cells. That way the new body where it would get installed won’t reject it.

In the near future, there’s a chance we could have humans with the hearts of pigs!

Wood Frog Dies and Comes Back to Life

By Anupum Pant

Ice Kills

Everybody knows what extremely low temperatures can do to our body. If you aren’t well protected from the cold, unable to retain the heat, the core temperature of your body may drop below 35 degree C and can cause some serious problems, even death.

At even lower temperatures, ice crystals can form in the tissues and puncture blood vessels. Ice crystals may even squeeze, deform and break cells. Otherwise it can leave behind shrunken and destroyed cells by sucking out water from them to form ice. Probably leaving you with a permanently damaged body part.

Due to ice formation inside the cells, this disastrous structural damage that is caused in human bodies, or most other organisms is unavoidable. We were not built to endure horrendous cold. But there are a few organisms who are built to live, or if I may say, die and then live again in extremely cold temperatures.

Meet the Wood Frog

Wood frog, a small variety of frog found in north america is one such creature. You ask what’s so interesting about them?

It is probably one of the most freeze tolerant beings. In other words, extracellular freeze tolerance and intracellular freeze avoidance enables the frog to do what it does.

Well, when it is really cold out there in the Arctic circle or the upper parts of America, they can freeze themselves for weeks, even for months. It does this by first finding out if it is really cold out there. When it touches the first bits of winter snow, a signal sets off in its body and the signal starts the blood freeing process.

All the water is pulled away from the core of its organs and the water gets frozen. Putting all the organs in a shell of solid ice. The whole frog becomes hard as a rock and sits there like that for weeks. Till it sees the spring time.

The most amazing part is that, during this time, the frog doesn’t breathe, its heart stops beating and even kidneys stop functioning. In medical terms it could be called dead. In reality, it is only temporarily dead.

Just like a dead man – without a hear beat – walking.

And then spring comes. It thaws itself out without any cellular injury and starts jumping again. It dies in winter and comes back to life in the next season.

This is probably how carbonite from Star Wars works.

Hit the like button if you learnt something today.

He Lives With No Heart Beating in His Chest

By Anupum Pant

Imagine this…
You are a doctor. A patient comes to you complaining of something and now you need to check his heartbeat. You plug the stethoscope in your ears and confidently move the probe to touch the chest of this patient, only to find that there is no heart beating inside that chest! In medical terms, isn’t this a dead man walking?

The answer is no, he is as alive as we are.  Medical technology has made it possible for a man to live without a traditional beating heart. Two incredible doctors, Billy Cohn & Bud Frazier, in the year 2011, replaced Craig A. Lewis’s lifeless heart with a revolutionary artificial device – A device that can replace your heart and lets the blood flow continuously – without a beat. By all criteria that doctors use to analyse patients, Craig is dead.

Side note: Do read about that scientist who died and came back to life – [Is There a Scientific Explanation for Everything?]

There is no beating when it works. Through a stethoscope, a doctor would probably hear a continuous whistling of blood sluicing through synthetic pipes and motors (I’m not sure about that). The two doctors had been testing it on cattle and it was their only hope to save Craig’s life. So, they decided to do it – replace his heart with this revolutionary device.

Related article: A heart that runs on nuclear energy – [Nuclear powered pacemakers for the heart]

Yes, technically you could say Craig A. Lewis is a heartless guy, but this is a serious leap in medical technology we are talking about here.

You cannot miss this very-short BBC documentary – “Heart Stop Beating” – where both the doctors talk about how they did something that had never been done before. [Video]

Heart Stop Beating | Jeremiah Zagar from Focus Forward Films on Vimeo.

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